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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 22.12
Human Site: S153 Identified Species: 32.44
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 S153 E F I P K G G S T S R L S N V
Chimpanzee Pan troglodytes XP_001136622 741 82148 S153 E F I P K G G S T S R L S N V
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 S153 E F I P K G G S T S R L S N V
Dog Lupus familis XP_543150 987 105833 S399 E F I P K G G S T S R L S N V
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 G140 P G M S L S A G S S P L H S P
Rat Rattus norvegicus XP_002724835 883 95283 S295 E F I P K G G S T S R L S N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 P157 S H P S M G G P A T A G L A P
Chicken Gallus gallus XP_417120 757 83269 T170 F I P K G G S T S R L S N V S
Frog Xenopus laevis NP_001128699 631 68072 T80 A V Y S Q A V T P V G S K K V
Zebra Danio Brachydanio rerio XP_002666687 799 86684 V212 N P A A S E F V P K G A P R M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 A157 M L A L Q K T A S I A S V T I
Honey Bee Apis mellifera XP_623553 607 67474 T56 L D S Q K K V T A S P E F V P
Nematode Worm Caenorhab. elegans P34653 632 71182 S81 V N Q F A Q L S I H D V P H Q
Sea Urchin Strong. purpuratus XP_796055 760 83393 P172 P G V P E F V P R P L S Q G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 N128 V N S S L V N N N N N N S N I
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 G105 A A P F T P R G V G T S T P T
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 13.3 100 N.A. 13.3 6.6 6.6 0 N.A. 0 13.3 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 33.3 100 N.A. 20 26.6 20 6.6 N.A. 26.6 20 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 7 13 7 7 7 7 7 13 0 13 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 32 0 0 0 7 7 0 0 0 0 0 7 0 0 0 % E
% Phe: 7 32 0 13 0 7 7 0 0 0 0 0 7 0 0 % F
% Gly: 0 13 0 0 7 44 38 13 0 7 13 7 0 7 0 % G
% His: 0 7 0 0 0 0 0 0 0 7 0 0 7 7 0 % H
% Ile: 0 7 32 0 0 0 0 0 7 7 0 0 0 0 13 % I
% Lys: 0 0 0 7 38 13 0 0 0 7 0 0 7 7 0 % K
% Leu: 7 7 0 7 13 0 7 0 0 0 13 38 7 0 0 % L
% Met: 7 0 7 0 7 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 7 13 0 0 0 0 7 7 7 7 7 7 7 38 0 % N
% Pro: 13 7 19 38 0 7 0 13 13 7 13 0 13 7 19 % P
% Gln: 0 0 7 7 13 7 0 0 0 0 0 0 7 0 7 % Q
% Arg: 0 0 0 0 0 0 7 0 7 7 32 0 0 7 0 % R
% Ser: 7 0 13 25 7 7 7 38 19 44 0 32 38 7 13 % S
% Thr: 0 0 0 0 7 0 7 19 32 7 7 0 7 7 7 % T
% Val: 13 7 7 0 0 7 19 7 7 7 0 7 7 13 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _